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Contraindicated. CYP3A4 is accountable for the development and elimination of cariprazine's Energetic metabolites. The impact of CYP3A4 inducers on cariprazine exposure hasn't been evaluated as well as the net outcome is unclear.pentobarbital will decrease the level or outcome of eltrombopag by impacting hepatic enzyme CYP2C9/10 metabolism. Use War